Metatrol – Human Supplement – (FWGE)


It’s the (Fermented Wheat Germ Extract) FWGE for everyone!

  • The most potent Fermented Wheat Germ Extract (FWGE) dietary supplement ever produced.
  • The only FWGE that is gluten-free
  • Just two capsules are equal to 5.5 g of AveUltra®.
  • Okay for you to take any time of day.

Since it was first introduced in the USA over 12 years ago, Fermented Wheat Germ Extract (FWGE) has been amazing researchers, impressing doctors, and satisfying consumers. Now, the most potent and super-concentrated form of FWGE is available, and research shows that it’s better than ever!


Prices exclude vat and delivery


Metatrol® – A Miracle of Nature for you. Impressive Research for your Doctor.

Dog Gone Pain UK Ltd is an exclusive distributor for American Biosciences products for HUMAN and Pet supplements including Metatrol, ImmPower, DGP and NK9.

New Metatrol®  is the “next generation of Fermented Wheat Germ Extract (FWGE)”; the most potent and super-concentrated FWGE in just two gluten-free capsules.

More than 40 research articles have been published in peer-reviewed medical journals describing FWGE’s efficacy and remarkable health benefits in a wide range of serious health challenges*.

Research shows that FWGE helps to:

  • Redirect energy to healthy cells for renewed vitality, well-being, and enhanced quality of life.*
  • Support optimal immune system function.*
  • Promote cell metabolic regulation.*
  • Maintain healthy appetite, weight, and cell mass.*

Although these sound like benefits only a doctor can appreciate, they are benefits you can actually feel!* Imagine your immune system working at peak performance, with enhanced energy, quality of life, a healthy appetite, and overall well-being of the body, mind, and spirit.*

Try these super-concentrated, powerful Metatrol® capsules to help keep your immune system strong, so that you can fight back!*

What is Fermented Wheat Germ Extract (FWGE)?

Met-Figure-1A Marvel of Science!

Medical researchers have long known that stress and injury can alter cellular metabolism and weaken immune system regulation, leading to serious health complications. Nobel Laureate, Dr. Albert Szent-Gyorgyi, published research in the 1980s showing that compounds found in very minute quantities in wheat germ could help restore healthy cellular metabolic function.* Fermented Wheat Germ Extract (FWGE) was created when a process was developed to concentrate these compounds by fermenting wheat germ with baker’s yeast.

A Miracle of Nature!

American BioSciences first introduced FWGE to the United States in 2005, and it’s been amazing researchers, impressing doctors, and satisfying consumers ever since. More than 40 articles have been published in peer-reviewed medical journals describing hundreds of studies with FWGE in cell lines, in animals, and in human clinical trials showing safety and efficacy. Research shows that FWGE helps to provide remarkable health benefits for a wide range of serious health challenges.*

Why is Metatrol® the next generation of FWGE and how is it different from AvéULTRA® or other FWGE products?

The “BioActive Fraction”

Extensive research on FWGE drew the attention of scientists at a leading NCI-designated academic research center. They invited American BioSciences to join a research collaboration to identify the individual molecules in FWGE that account for its biological activity, and find the “bioactive fraction”. This research collaboration determined:

  • In its natural form, FWGE consists of thousands of molecules, but 100 percent of the biological activity and health benefits are provided by less than 100 molecules which compose the “bioactive fraction.”
  • Non-active molecules dilute FWGE bioactives, and they include gluten and gliadin, which may contribute to unwanted inflammation.

American BioSciences developed a patent-pending combination of technologies used in food processing, which concentrates the“bioactive fraction,” referred to as Fermented Wheat Germ Extract–Super Concentrate™ (FWGE-SC). Non-active molecules, including gluten, are excluded. Studies show that 41 mg of FWGE-SC, found in Metatrol®, has the same biological effect as 5,500 mg of pure FWGE, found in AvéULTRA®, and 17,000 mg of spray dried FWGE, found in original Avé®. (Fig. 1)

Additional information

Weight 0.1000 g

Ingredients and Usage

As a dietary supplement for adults, take 2 Metatrol® capsules per day (before, during or after meals, as preferred). For people weighing over 200 lbs, take 4 Metatrol® capsules per day.

Caution: KEEP OUT OF REACH OF CHILDREN. Should not be taken during pregnancy or while nursing. Consult with a healthcare professional for recommended usage levels for children and guidance using more than 4 Metatrol® capsules per day. Do not consume Metatrol® if you are taking immune suppressive medication. This product is manufactured with wheat germ and baker’s yeast. Use cautiously if sensitive to these ingredients. Gluten and gliadin are removed, so that this product is gluten-free.  This product is vegetarian-friendly.

This product is not intended to be the sole source of nutrients in the diet. This product is not affected by temperatures under 122° F (50° C). Best if stored in a dry place at temperatures less than 80° F (26 °C).



Click here for Third Party Research Information Third Party Articles Describing Fermented Wheat Germ Extract Research

How Does FWGE Work


1. FWGE Supports Cell Metabolic Regulation

Fermented Wheat Germ Extract helps to regulate healthy cellular metabolism with the proper utilization of oxygen and glucose leading to enhanced mitochondrial function.*

2. FWGE Promotes Immune System Regulation

Enhances the ability of T-cells to respond to antigen presentation, and B-cells to respond to activation and produce appropriate antibodies*
Normalizes balance of cellular and hormonal (Th1/Th2) immune function*
Enhances macrophage functioning*

3. FWGE Enhances NK Cell Targeting

Helps the immune system identify invaders for attack. Immune system enemy invaders try to hide from the immune system’s Natural Killer (NK) cells by displaying a surface molecule called MHC-1. MHC-1 tells NK-cells, “Don’t attack me, I’m one of the good guys”, but, research shows FWGE suppresses the invading cell’s “mask” (MHC-1), resulting in increased NK-cell targeting and immune system clearing.* Natural cancer fighting substances may use this same kind of identification process to destroy cancer cells.